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Dentomaxillofacial Radiology, Vol 30, Issue 1 14-21, Copyright © 2001 by British Institute of Radiology


ARTICLES

High-resolution magnetic resonance imaging of squamous cell carcinoma of the tongue: an in vitro study

A. Tetsumura, N. Yoshino, T. Amagasa, K. Nagumo, N. Okada and T. Sasaki
Department of Oral and Maxillofacial Radiology, Graduate School, Tokyo Medical and Dental University, Tokyo, Japan.

OBJECTIVES: To determine in vitro the potential of high-resolution MRI for evaluating the depth of tumor invasion of the tongue. METHODS: Twenty-one resected specimens of squamous cell carcinoma of the tongue were examined on a 1.5T MRI system with a 4 cm surface coil using four different sequences; T1W SE, T2W SE, 3D-FISP and 3D-CISS. The thickness of normal epithelium, tumor depth and width were measured on both MR images and histopathological sections. RESULTS: The mucosal epithelium, lamina propria and muscles of the tongue were clearly identifiable on MRI. All 21 carcinomas, including three early invasive carcinomas, were clearly demonstrated. A high correlation was found between the values measured by MRI and histopathology for thickness of mucosal epithelium and both depth and width of tumors. There was a good agreement between the T2W SE and the other imaging sequences for measurements of both depth and width of tumors. CONCLUSION: High-resolution MR imaging appears reliable for the in vitro evaluation of depth of tumor invasion in carcinoma of the tongue.


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P. Lam, K. M. Au-Yeung, P. W. Cheng, W. I. Wei, A. P.-W. Yuen, N. Trendell-Smith, J. H. C. Li, and R. Li
Correlating MRI and Histologic Tumor Thickness in the Assessment of Oral Tongue Cancer
Am. J. Roentgenol., March 1, 2004; 182(3): 803 - 808.
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