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Polymorphous low grade adenocarcinoma presenting an uncommon radiographic aspect

¹ Department of Oral Pathology, School of Dentistry, University of São Paulo, Brazil; ² Department of Head and Neck Surgery, School of Medicine, University of São Paulo, Brazil

*Correspondence to: Dr Marina Magalhães, Av professor Lineu Prestes 2227, Departamento Patologia Bucal, 05508-900, São Paulo- SP, Brazil; Email: mhcgmaga{at}usp.br

Received 10 February 2005; revised 12 July 2005; accepted 24 July 2005

The aim of this study was to present clinical, histological and immunohistochemical aspects of a polymorphous low grade adenocarcinoma occurring in the mandible. A radiolucent tumour, located in the right mandible, was removed from a 40-year-old woman. Radiographic and CT exams revealed that the lesion expanded bucco-lingual cortical plates and presented an irregular scalloping of the bone. The surrounding lining mucosa was intact. The patient underwent total surgical removal of the lesion with an intraoperative biopsy. Histological diagnosis was polymorphous low-grade adenocarcinoma confirmed by immunohistochemical study. One-year follow up was uneventful. The accurate diagnosis of lesions presenting unusual clinical aspects, as the one presented here, is critical for correctly handling treatment.

Keywords: polymorphous low grade adenocarcinoma; salivary gland neoplasm; immunohistochemistry; radiography