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Dentomaxillofacial Radiology (2007) 36, 526-529
© 2007 British Institute of Radiology
doi: 10.1259/dmfr/71449570

CASE REPORTS

Clinical, pathological and radiological evaluation of disseminated Langerhans' cell histiocytosis in a 30-month-old boy

E Baltacioglu*,1, FÇ Senel2, B Özen3, AD Ofluoglu4, S Ersöz5, R Kebudi6 and H Tanyeri4

1 Department of Periodontology, Faculty of Dentistry, Karadeniz Technical University, Trabzon, Turkey; 2 Department of Oral and Maxillofacial Surgery, Faculty of Dentistry, Karadeniz Technical University, Trabzon, Turkey; 3 Department of Pediatric Dentistry, Faculty of Dentistry, Karadeniz Technical University, Trabzon, Turkey; 4 Department of Oral and Maxillofacial Surgery, Faculty of Dentistry, Istanbul University, Istanbul, Turkey; 5 Department of Pathology, Faculty of Medicine, Karadeniz Technical University, Trabzon, Turkey; 6 Department of Pediatric Oncology, Faculty of Medicine, Istanbul University, Turkey

*Correspondence to: Dr Esra Baltacioglu, Department of Periodontology, Faculty of Dentistry, Karadeniz Technical University, 61100 Trabzon, Turkey; Email: baltaciogluesra{at}yahoo.com

Received 17 August 2006; revised 26 December 2006; accepted 3 January 2007

Langerhans' cell histiocytosis is a rare disease characterized histologically by the proliferation of Langerhans' cells. Oral involvement is frequent and the disease simulates severe localized periodontitis. In this report, we present a case of disseminated Langerhans' cell histiocytosis in a 30-month-old boy who had a mass covering the entire maxillopalatine region and suffered severe periodontal destruction in the posterior maxilla and mandible. We discuss the radiological, histopathological and immunohistochemical findings.

Keywords: Langerhans' cell histiocytosis; periodontitis; radiology






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