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Dentomaxillofacial Radiology (2008) 37, 52-57
© 2008 British Institute of Radiology
doi: 10.1259/dmfr/89572785

CASE REPORT

Giant facial haematoma in neurofibromatosis type 1

Z J Sun1,2, Y F Zhao1, S P Wang3 and S G He1,2

1 Department of Oral and Maxillofacial Surgery, Wuhan University, Hubei, China; 2 Key Laboratory for Oral Biomedical Engineering of the Ministry of Education, Wuhan University, Hubei, China; 3 Department of Oral Radiology, School and Hospital of Stomatology, Wuhan University, Hubei, China

Department of Oral and Maxillofacial Surgery, School and Hospital of Stomatology, Wuhan University, 237 Luo Yu Road, Wuhan, Hubei, China 430079; E-mail:sangang{at}public.wh.hb.cn

Department of Oral and Maxillofacial Surgery, School and Hospital of Stomatology, Wuhan University, 237 Luo Yu Road, Wuhan, Hubei, China 430079; E-mail:sangang{at}public.wh.hb.cn

Received 29 August 2006; revised 27 January 2007; accepted 8 March 2007

Neurofibromatosis type 1 (NF1) is an inherited autosomal dominant disorder. Haematoma is an unusual complication of neurofibromatosis and extremely rare in the maxillofacial region. A case of haematoma in NF1 of the left face is presented. MR images of acute haematoma in NF1 and radiographic features of the mandible are described. Stenosis of the internal jugular vein was noted in MR angiography (MRA). Surgical resection of the tumour and evacuation of blood clots were performed. Histological and immunohistochemical examination demonstrated that the neurofibroma tumour cells infiltrated the mural layer of vessels without malignant translation. MRI is a good choice for depicting haematoma in neurofibromatosis. Intratumour haemorrhage may result from the infiltration of vessels into the lesion and minor trauma on the affected area.

Keywords: neurofibromatosis type 1; haematoma; magnetic resonance imaging; computed tomography; panoramic radiography






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