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Rhino-orbito-cerebral mucormycosis: report of two cases and review of the literature

Ankara University, Faculty of Medicine, Department of Radiology Ankara, Turkey

*Correspondence to: Nuray Haliloglu, MD, University of Ankara, Faculty of Medicine, Department of Radiology, Ibni Sina Hospital, 06100 Ankara, Turkey; E-mail: nurayunsal2{at}hotmail.com

Received 25 April 2007; revised 31 May 2007; accepted 31 May 2007

Rhino-orbito-cerebral mucormycosis (ROCM) is a rare, fulminant opportunistic fungal infection that is mostly seen in immunocompromised or diabetic patients. The disease should be recognised and treated immediately. We present here MR imaging findings of two patients with histopathologically proven ROCM. One of the cases had a history of corticosteroid treatment and iatrogenic diabetes mellitus and although amphotericin B was started immediately, the disease progressed and surgical debridement was necessary. The second case was a patient with diabetes mellitus type 1 in whom ROCM had occurred following an abdominal surgery; amphotericin B treatment alone was adequate in this patient.

Keywords: orbit; magnetic resonance imaging; mucormycosis