DMFR
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
This Article
Right arrow Figures Only
Right arrow Full Text
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Similar articles in this journal
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrow reprints & permissions
Google Scholar
Right arrow Articles by Ribeiro, D A
Right arrow Articles by Angelieri, F
PubMed
Right arrow Articles by Ribeiro, D A
Right arrow Articles by Angelieri, F
Dentomaxillofacial Radiology (2008) 37, 404-407
© 2008 British Institute of Radiology
doi: 10.1259/dmfr/58548698

RESEARCH

Cytogenetic biomonitoring in patients exposed to dental X-rays: comparison between adults and children

D A Ribeiro*,1, G de Oliveira2, GM de Castro1 and F Angelieri2

1Department of Biosciences, Federal Univesity of Sao Paulo, UNIFESP, Santos, Brazil; 2Department of Orthodontics, Sao Paulo Metodista University, UMESP, Sao Bernardo do Campo, Brazil

*Correspondence to: Daniel Araki Ribeiro, DDS, PHD, Departamento de Biosiências, Universidade Federal de São Paulo – UNIFESP, Av. Ana Costa 95, 11060-001, Santos – SP, Brazil. E-mail: daribeiro{at}unifesp.br

Received 19 September 2007; revised 10 December 2007; accepted 10 December 2007

Objectives: The aim of the present study was to comparatively evaluate the DNA damage (micronucleus) and cellular death (pyknosis, karyolysis and karyorrhexis) of exfoliated buccal mucosa cells from children and adults following dental X-ray exposure.

Methods: A total of 17 adults and 17 children submitted to panoramic dental radiography were included in this study.

Results: The results indicated no statistically significant differences (P > 0.05) in children's micronucleated oral mucosa cells before and after dental X-ray exposure. In the same way, no mutagenic effects were observed in adults following X-ray exposure. On the other hand, X-rays increased other nuclear alterations closely related to cytotoxicity such as karyorrhexis, pyknosis and karyolysis in both groups. The comparative analysis between children and adults demonstrated no statistically significant differences in micronucleus frequency or cytotoxicity (P > 0.05).

Conclusions: In summary, these data indicate that dental paroramic radiography may not be a factor that induces chromosomal damage, but it is able to promote cytotoxicity. It seems that children are not more susceptible to the noxious activities induced by X-rays when compared with adults.

Keywords: buccal mucosa cells; X-ray; micronucleus test






HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
BJR DMFR IMAGING ALL BIR JOURNALS
Copyright © 2008 by the British Institute of Radiology.