Interpretation of scintigraphic findings of oral malignant tumours with a new scanning agent of technetium-99m-hexakis-2-methoxy-isobutyl-isonitrile (Tc-99m-MIBI)
T Sato*,1,
Y Kawabata1,
Y Saigo2,
Y Iwashita1,
S Suenaga1,
H Indo1,
S Hamahira1,
K Kawano1,
T Nitta3,
Y Morita4,
HJ Majima1 and
K Sugihara3
1 Field of Oncology, Department of Maxillofacial Radiology, Kagoshima University Graduate School of Medical and Dental Sciences, Kagoshima, Japan;
2 Division of Clinical Engineering, Kagoshima University Hospital, Kagoshima, Japan;
3 Field of Oral and Maxillofacial Rehabilitation, Department of Oral and Maxillofacial Diagnostic and Surgical Sciences, Kagoshima University Graduate School of Medical and Dental Sciences, Kagoshima, Japan;
4 Department of Oral Radiology, Tsurumi University School of Dental Medicine, Tsurumi, Japan
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Figure 1 Two curves showing radioactive count of Tc-99m-MIBI after injection in tumour and control. (A) Early dynamic scan was performed for 5 min immediately after injection. (B) Early static scan was carried out 10 min after injection. (C) Delayed dynamic and (D) static scans were performed 2.5 h after injection. Blood flow index (F/E) was obtained from early dynamic scan from 30 s to 120 s after injection. Early retention index (H/G) was obtained from early dynamic scan from 4 min to 5 min after injection, and delayed retention index (J/I) was obtained from delayed dynamic scan 2.5 h after injection. Tumour retention index was calculated from early and delayed retention indexes
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Figure 2 A 71-year-old man with squamous cell carcinoma in the left tongue. Early static scan of Tc-99m-MIBI scintigraphy showing hot uptake in the tumour region (A, arrow). Uptake decreased in the delayed static scan (B)
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Copyright © 2006 by the British Institute of Radiology.
