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Correlation between histopathological image and radiographic image pattern in fibro-osseous lesions in relation to bone complexity and distribution

M Araki*,1,4, S Kawashima1,4, N Matsumoto2,5, S Nishimura3,5 and K Komiyama2,5

1Department of Oral and Maxillofacial Radiology, Nihon University School of Dentistry, Tokyo, Japan; 2Department of Pathology, Nihon University School of Dentistry, Tokyo, Japan; 3Department of Oral and Maxillofacial Surgery, Nihon University School of Dentistry, Tokyo, Japan; 4Division of Advanced Dental Treatment, Dental Research Center, Nihon University School of Dentistry, Tokyo, Japan; 5Division of Immunology and Pathobiology, Dental Research Center, Nihon University School of Dentistry, Tokyo, Japan


Figure 1
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  		Figure 1 Radiographs of clinical cases were classified into 5 patterns. (a) Focal pattern, radiopacity with uniformity (case 14); (b) target pattern, central radiopacity within radiolucent area (case 8); (c) lucent pattern, well-defined radiolucent area (case 18); (d) calcification pattern, calcified flecks or scattered within radiolucent area (case 3); (e) multiconfluent pattern, radiopacity with mottled pattern (case 6)

 

Figure 2
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  		Figure 2 a) Histopathological examination of a tiling image in the central area of a case (target pattern ) used in this study (magnification x20; haematoxylin and eosin). (b) Binary image divided by the threshold, directly confirming whether bone tissue or fibrous connective tissue is present at the site of the histopathological image

 

Figure 3
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  		Figure 3 Binary image of a target pattern divided into 25 equal areas, comprising 16 marginal areas, 8 middle areas and 1 central area

 




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